Biomedical Imaging Research Unit

MetaSystems VSlide slide scanner


  • Whole section scanning
  • Region of interest scanning including setting up a scan field (region of interest) at low magnification and then scanning the ROI at higher magnifcation/resolution.
  • Tissue microarray scanning and on the fly analysis
  • Brightfield, high resolution brightfield (using the monochrome camera) or fluorescence


CoolCube1 (colour & monochrome)



  • Zeiss Axio Imager Z2 fully motorised microscope
  • Egonomic driver for XY control
  • Automated 80 slide feeder
  • Objectives: Dry (2.5x/0.075 NA, 10x/0.45 NA, 20x/0.9 NA, 40x/0.95 NA) Oil (40x/1.3 NA, 63x/1.4 NA)
  • Automated oiler module
  • Marzhauser Motorised 5 position scanning stage
  • MetaCyte acquisition software and stitching
  • On the fly TMA (tissue microarray) analysis
  • Fluorescence filter sets for DAPI, FITC, TxRed, Cy5 and triple viewing set. Details available in document below.


If you want to see some examples which illustrate what can be done with this system, please take a look at the movies below which were created by Luke Hammond from QBI Microscopy using his VSlide.

Support files

ImageJ macros for cropping borders from extracted images:

(1.0 kB, TEXT)
(994.0 bytes, TEXT)
Using the ImageJ macros
(276.6 kB, PDF)

IrfanView - Instructions for cropping extracted images
This document explains how to use open source software IrfanView to crop off the white/black boxes from extracted images. (740.1 kB, PDF)

Funded by

Successful grant application by Professor Mike Dragunow (Dept of Pharmacology & Centre for Brain Research) to Gravida: National Centre for Growth and Development


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