Biomedical Imaging Research Unit

Fluxion BioFlux 200

Dr Jo James, Lecturer in the Department of Obstetrics and Gynaecology, used a BioFlux 200 flow system extensively in her research while based in the UK. Funding to purchase the BioFlux 200 was provided in 2014 through the Department of Obstetrics and Gynaecology. The system is now available for use by interested researchers.

The BioFlux 200 is designed to run multiple channels of cells under laminar shear stress simultaneously, and can be used in combination with the Nikon TE2000E inverted microscope to image the response of cells to shear stress over time.

It has also been used to quantify migration and apoptosis and has other applications such as rolling adhesion assays. The main benefits are that it can run multiple replicates at different levels of shear stress allowing for experiments to be accurately controlled, or for multiple cell preparations to be assayed simultaneously.

Specialised plates with integrated flow cells are required.

More specifications can be found on the Fluxion website.

 

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Mark Stafford, from Carl Zeiss Australia, provides training in the use of the BioFlux 200

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Fluxion BioFlux 200

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BioFlux Plate in position on the Nikon TE2000E fluorescence microscope

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