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Biomedical Imaging Research Unit

Welcome!

The Biomedical Imaging Research Unit (BIRU) is a Research Platform that provides shared research infrastructure, training and support. It is located in the Faculty of Medical and Health Sciences at the Grafton campus.

Hilary Holloway Prize for Best Image 2024
'When Van Gogh gets under your skin', Darven Murali Tharan, Faculty of Science Reveals the organisation of collagen fibres in biological tissue showcasing the orientation and distribution of collagen fibres in human skin, taken in vivo. The data was taken using polarisation-sensitive optical coherence tomography (PS-OCT).

BIRU feedback

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We are always keen to hear what people think about the BIRU.

Please use the QR code to provide us with feedback on your experience.

We also welcome your ideas and opinions on subjects such as:

  • Training and support
  • Instrumentation
  • Seminars and workshops
  • New Olympus FV4000 upright confocal microscope
    23 January 2025
    There is a new confocal microscope in the BIRU! The system is a FLUOVIEW Olympus FV4000. It is an upright confocal microscope with the most sensitive detector technology on the market. It can image standard fluorophores as well as near-infrared/ far-red signals. It has a point scanner for detailed imaging and a resonant scanner for fast live cell/ large volume imaging. Heating and cooling are also available.
  • Annual image competition - results - 2024
    20 December 2024
    The winner of the 2024 BIRU image competition and recipient of the Hilary Holloway Prize is Darven Murali Tharani from the Faculty of Science. Their entry in the Visualisation category is entitled 'When Van Gogh gets under your skin'. The image reveals the organisation of collagen fibres in biological tissue showcasing the orientation and distribution of collagen fibres in human skin, taken in vivo. The data was taken using polarisation-sensitive optical coherence tomography (PS-OCT). Winners were selected for each of the 4 categories and 4 images received highly commended awards. There was also one special mention award for 2024.
  • Light sheet fluorescence microscopy comes to BIRU
    09 December 2024
    A new PhaseView Alpha 3 Facility Edition light sheet fluorescence microscope has recently been installed in BIRU. The system has a wide variety of objective lenses suitable for imaging both optically cleared fixed samples and live samples such as zebrafish embryos. There are 6 excitation lasers and 6 separate filter sets. An Okolab incubation system is available that can provide heating and 5% carbon dioxide. The system is designed for core facilities and most functions are motorised for ease of use. Calibration using the preferred immersion medium is required in advance of using the system in order to align the light sheet arms. The software is quite straightforward to use and Imaris is available for advanced visualisation and quantification. A separate high specification PC is available for this purpose. For a full list of specifications, please check out the system page.

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