School of Medical Sciences

Research - areas of interest

The research being undertaken in the department includes:

  • chemical and anatomical changes and molecular mechanisms of nerve cell death in the human brain in Alzheimer's disease, Huntington's disease, Parkinson's disease, Schizophrenia and Epilepsy
  • stem cells and neurogenesis in the human brain
  • molecular mechanisms of neurodegeneration
  • fetal neural grafts in animal models of neurodegenerative diseases of the brain
  • comparative neuroanatomy of the avian brain; neural control of vocalization
  • neurothology: research on how nervous systems generate vocalisation behaviour
  • modelling of heart function using MRI
  • MRI imaging of the pelvic diaphragm and anal sphincter mechanism
  • imaging of the small bowel
  • use of novel contrast agents in liver MRI
  • structure and function correlations between high resolution CT of the chest and lung disease
  • role of primary cilia in mechanosensation in cartilage
  • role of the primary cilium in the development of renal fibrosis and polycystic kidney disease
  • the role of the primary cilium in epithelial-to-mesenchymal transition
  • cytoskeleton and effects of asbestos in living cells
  • engineering elastin-rich tissues
  • role of the extracellular matrix in ischaemic heart disease
  • articular cartilage - molecular anatomy, mechanobiology and biochemistry of development, differentiation and osteoarthritic degeneration
  • developmental biology - patterning of the limb and growth plate
  • interstitial lung disease
  • kidney disease and transplantation
  • scrotal ultrasound in asymptomatic post-vasectomy patients
  • therapeutic embolisation for acute haemorrhage in the abdomen and pelvis
  • geometry of the human hip joint and the design of prostheses
  • modelling the gastro-oesophaegal junction
  • hepatotoxicity
  • development of a technique to identify epithelial cells for use in forensic casework.