Pipelle for Pregnancy in IVF (PIP-IVF)

Study design

The PIP-IVF study is a randomised controlled trial in women undergoing IVF or frozen-thawed embryo transfer with their own eggs.

Eligible women who consent to participate in the trial will be randomised to either

  1. An endometrial pipelle sampling procedure
  2. No procedure

There is a 50/50 chance that women will be randomised to each arm. The allocation occurs completely at random and participants are not able to chose their allocation or change the allocation.

Women who are randomised to undergo the endometrial pipelle procedure will be scheduled in for a 20 minute appointment in the fertility clinic approximately one month before the planned date of embryo transfer. If you are interested in participating in PIP-IVF, please contact us as soon as you know what month your IVF/ICSI cycle or embryo transfer is planned for.

Eligibility criteria

Women are eligible for the PIP-IVF study if they:

  1. Are planning to undergo IVF/ICSI/embryo transfer with their own eggs
  2. Have not had any of the following within 3 months of their IVF cycle/embryo transfer:
    • hysteroscopy
    • hysterosalpingogram (HSG)
    • endometrial biopsy
    • laparoscopy
    • surgically managed miscarriage
  3. Have not participated in another trial in the last 30 days

For more information about the PIP-IVF trial, please read the information leaflet

If you are interested in participating in the PIP-IVF study or would like to know more, please contact us as soon as possible

Sarah Lensen – PIP study coordinator

09 923 9487