School of Medicine

MDSG topics

Premenstrual syndrome (includes cyclical mood swings and premenstrual exacerbation of symptons)

                                                                                                                                            [R] = Review

                                                                                                                                            [P] = Protocol

Prevention and treatment

Medical Treatment

  • Anorexiants
  • Bromocriptine
  • Clonidine
  • Danazol
  • Diuretics
  • Dopamine
  • Essential fatty acids (eg, evening primrose oil)
    [P] Evening Primrose Oil or other essential fatty acids for the treatment of pre-menstrual syndrome (PMS)
  • Gonadotrophin releasing hormones
  • Hormones
    [P] Progesterone for premenstrual syndrome
  • Minerals, supplements, or herbal treatments (eg, magnesium)
    [P] Vitex agnus castus for premenstrual syndrome
  • Nonsteroidal anti-inflammatory drugs
  • Oral contraceptive pill
  • Psychotropic drugs (eg, antidepressants, anti-anxiety agents, tranquillisers)
  • Vitamins
    [P] Vitamin B6 for premenstrual syndrome
  • Other medications


  • Hysterectomy (with and without bilateral salpingo-oophorectomy)

Psychological Interventions

  • Relaxation



Alternative therapies

  • Acupuncture
  • Biofeedback
  • Reflexology