School of Medicine

MDSG topics

Evaluation of subfertility treatments relating to the male partner

                                                                                                                                            [R] = Review

                                                                                                                                            [P] = Protocol

Idiopathic oligo- astheno- teratospermia

Medical therapies

  • Antioestrogens
    [R] Clomiphene or tamoxifen for idiopathic oligo/asthenospermia
  • Androgens
    [R] Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia
  • Bromocriptine
    [R] Bromocriptine for idiopathic oligo/asthenospermia Kinin- enhancing drugs (kallikrein)
    [R] Kinin-enhancing drugs for unexplained subfertility in men
  • Other medical treatments
  • Artificial insemination by husband (AIH)
  • Assisted conception techniques

Oligospermia associated with varicocele

Medical therapies


  • "Curative" varicocele treatment
    [R] Surgery or embolisation for varicocele in subfertile men
  • Preventative varicocele treatment

Artificial insemination by donor (DI)

  • Type of semen used (fresh or frozen)
  • Site of insemination (intracervical or intrauterine)
    [R] Intra-uterine versus cervical insemination of donor sperm for subfertility
  • Timing and number of inseminations
  • Cryopreservation methods

Infertility associated with antisperm antibodies

Medical therapies

  • Immuno modulating drugs (including steroids)
  • Treatment of antibody containing sperm samples
  • Artificial insemination
  • Assisted conception techniques


Medical therapies

  • Psychological interventions

Hypogonadotropic hypogonadism

  • Weight adjustment
  • Psychological interventions
  • Drug treatment

Assisted conception techniques for male infertility

  • Sperm preparation techniques
    [R] Semen preparation techniques for intrauterine insemination
  • Micro manipulation techniques
    [R] Intra-cytoplasmic sperm injection versus conventional techniques for oocyte insemination during in vitro fertilisation in patients with non-male subfertility
  • Intrauterine insemination
    [R] Timed intercourse versus intra-uterine insemination with or without ovarian hyperstimulation for subfertility in men
    [R] Single versus double intrauterine insemination (IUI) in stimulated cycles for subfertile couples
  • Sperm Retrieval Techniques
    [R] Techniques for surgical retrieval of sperm prior to ICSI for azoospermia


  • [P] Zinc for male subfertility