School of Medical Sciences

Human Neurodegenerative Diseases Group - facilities / technology

  • Human Brain Bank (4-80ยบ freezers)
  • Human tissue processing laboratory (microtome)
  • Receptor autoradiography laboratory (cryostat)
  • Immunhistochemistry laboratory
  • In situ hybridisation laboratory
  • Confocal microscopy and video enhanced microscopy
  • Electron microscopy
  • Fluorescence microscopy and image analysis
  • High-Content Screening Platform (Discovery-1 automated microscope; Fluostar spectrofluorometer; Embla 96-well plate washer)
  • Molecular (Western blotting, EMSAs, IPs, etc) and Cellular (intracellular injection and digital time-lapse microscopy) Biology Laboratories.
  • Tissue Culture Platform (focusing upon human cell systems where possible).

We are currently developing human dissociated astrocytic and microglial cultures (and slice cultures) from adult biopsy and post-mortem human brain.