Centre for Brain Research


Molecular Neurotherapeutics

Working together to improve lives

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Principal Investigator - Associate Professor Deborah Young

Our research interests are broad and range from the study of the molecular basis of learning and memory, to gene therapy of neurological disorders. The main common theme is the use of somatic cell gene transfer to study neuronal physiology and to treat human disease.

Our research covers the full spectrum from molecular biology through to animal behaviour and human clinical trials. For our gene therapy program, in the first instance "proof of principle" experiments are conducted to test therapeutic concepts in an attempt to obtain phenotypic correction in models of neurological disease.

Promising approaches are advanced to human clinical trials. Many of our research projects involve collaborations and our laboratory is of international standing and forms a key role in a major network of mammalian brain gene interventionists.

View Deborah's gene therapy research profile here

 

 

Team members


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Dr Alexandre Muravlev - Research Fellow

Dana Fong - Senior Research Technician

Dr Angela Woo - Post Doctoral Fellow

Jordi Boix-i-Coll - Behavioural unit Co-ordinator

Jason Michael - PhD candidate

Tiger Aspell - Master's degree student

Kathryn Van del Zanden - Master's degree student

Objectives


  • Develop antibody and gene based therapies for neurodegenerative disorders
  • Understand the underlying mechanisms of disease
  • Develop technologies to facilitate and support therapeutic approaches
 

Areas of interest


  • Viral vectors
  • Parkinson's disease
  • Alzheimer's disease
  • Huntington's disease
  • Learning & memory
  • Epilepsy
  • Vaccines for neurological disease
  • Effects of the environment on brain function and function
 

Acknowledgments


Publications


For a full list of publications, please visit Deborah Young's gene therapy research page here