CBR Clinical Seminar: Prion-like propagation of protein assemblies in neurodegenerative diseases Event as iCalendar

23 August 2018

10 - 11:30am

Venue: CBR Seminar Room

Location: 505-501 Faculty of Medical and Health Sciences

Host: Centre for Brain Research

Cost: Free

Contact email: sarah.j.evans@auckland.ac.nz

Prof Ronald Meilki

 

Professor Ronald Melki - Universite Paris-Saclay Institute of Neuroscience

Research area:
The accumulation of protein aggregates within the central nervous system is the hallmark of several progressive neurodegenerative disorders (e.g. Alzheimer, Parkinson, Huntington and Creutzfeldt-Jacob diseases). These aberrant protein conformers are the consequence of the misfolding and aggregation of specific proteins. We demonstrated recently that the protein aggregates that are tightly associated to pathology spread from cell to cell in a prion-like manner reminiscent of PrP in Creutzfeld-Jacob disease.