Do methamphetamine users show functional differences in the brain in response to risk? Event as iCalendar

30 October 2017

12 - 1pm

Venue: Room 505-364, FMHS

Location: 85 Park Road, Grafton

PharmaTell PhD Provisional Year Review Presentation

Sabrini Sabrini, PhD candidate, School of Pharmacy, the University of Auckland

Impulsivity and risk-taking behaviour have been proposed to be associated with drug use disorders and contribute to relapse. One of the most commonly abused drugs in New Zealand is methamphetamine, which is a potent psychostimulant but also neurotoxic. Impulsivity in methamphetamine dependence has been widely studied with delay discounting tasks that isolate reward processing. Meanwhile, risk-taking is commonly studied with gambling tasks that have the elements of both risk and reward. To this date, no study has investigated risk aversion and reward processing in active methamphetamine users. In this PhD project, we will collect brain and behavioural data from active methamphetamine users, abstinent methamphetamine subjects, and non-using controls, using fMRI paired with a modified monetary incentive delay task that has been designed to dissociate risk assessment from reward processing. Brain morphometry will also be used to examine the structural changes associated with methamphetamine use.

For more information, Please email Dr Sara Hanning.