Molecular Medicine & Pathology seminar: Universal sensor development and its application to bioimaging Event as iCalendar

17 February 2014

3:30 - 4:30pm

Venue: Seminar Room 501-505, Building 501, 85 Park Road, Grafton

The conventional bioprobe design has been carried out by so-called hypothesis-driven approach. The basic assumption of hypothesis-driven approach is that the scientist “knows the target” in advance, and then design the recognition motif for it. An alternative approach is diversity-driven approach, in which a broad range of fluorescence molecules in a library format are constructed by combinatorial chemistry, as a tool box for unbiased screening.Among several diversity sources, “Diversity Oriented Fluorescence Library Approach (DOFLA)” using fluorophore core with diverse recognition motives around has been the most fruitful in novel bioprobe generations. Using DOFLA, various colorful bioimaing probes based on BODIPY structure from stem cells to Neurons will be demonstrated.

Presented by: Professor Chang Young-Tae , National University of Singapore


For more information or you wanting to meet Professor Chang, please contact: Robyn McDonald Email: r.mcdonald@auckland.ac.nz