Auckland Cancer Society Research Centre seminar: The secret lives of cancer genes Event as iCalendar

14 February 2014

2 - 3pm

Venue: Seminar Room 503-024, Building 503, 85 Park Road, Grafton

Receptor tyrosine kinases are drug targets of proven efficacy in clinical oncology. The oncogenicity of this class of cancer genes is generally understood to be mediated by signals transduced from their canonical location on the plasma membrane.  This presentation will describe our serendipitous discovery that MET protein kinase localizes in the mitochondria of cancer cells.  Based on data that show effects of mitochondrial MET on mitochondrial functions, we propose a metabolic model of cancer fitness that may have a mechanistic role in the resistance of cancer cells to agents designed to inhibit receptor tyrosine kinases.

Speaker: Professor Oi-Lian Kon

For further information please contact Jack Flanagan .