Liggins Institute seminar: The placenta is a programming agent for cardiovascular disease Event as iCalendar

09 October 2013

4 - 5pm

Venue: Seminar Room 505-003, Building 505, 85 Park Road, Grafton

Some decades ago, Barker and colleagues showed that heart disease is inversely related to birthweight.  His team later showed that the risk is modified by placental weight.  Large or small placentas in relation to birthweight confer high risk for disease.  Recent evidence from several centers has shown that size and shape of the placenta highly influence the risk for many cardiovascular conditions as well as for many non-cardiovascular diseases including hypertension and several cancers. These findings point to a maternal-fetal interactions that characterize specific kinds of disease.  Maternal stature, BMI, and hip width appear to be markers for physiological conditions that modify placental structure and allow the prediction of disease. It is likely that the placenta has differing influences on the fetal cardiovascular system depending on stage of development.  Further work is needed to determine the biological role of placental phenotype in predicting adult onset disease.

Presented by: Dr. Kent Thornburg

Light refreshments provided

For more information, please contact: Elise Donovan , PhD Clint Gray , PhD Email: Email: Phone: +64 9 923 4776                                           Phone: +64 9 923 4785