PharmaTell seminar: Gene and drug delivery systems for the treatment and prevention of brain disorders and diabetes Event as iCalendar

10 June 2013

12 - 1pm

Venue: Room 505-364, Building 505, 85 Park Road, Grafton

Targeted nano-particulate systems hold extraordinary potential for the delivery of therapeutics across the blood brain barrier (BBB). An innovative approach of combining transferrin receptor targeting with enhanced cell penetration to design liposomal vectors for improving the transport of molecules into the brain will be presented and discussed. Diabetes afflicts roughly 250 million worldwide. The ability of the thermosensitve polymeric solution to provide basal level of insulin for three months after a single subcutaneous injection will be discussed. Further, a novel nanobiotechnology based non-viral DNA carrier for delivery of pDNA encoding IL-4 and IL-10 genes for prevention of type 1diabetes will be presented.

Jagdish Singh is Professor and Chair of the Department of Pharmaceutical Sciences at North Dakota State University. Singh’s research efforts focus on the mechanistic studies for developing and testing novel delivery technologies to deliver biotechnologically derived molecules (e.g., peptide, protein, and gene). He has published over 160 peer-reviewed papers and 280 abstracts. Singh received his Ph.D. form Banaras Hindu University, Varanasi, and completed post-doctoral fellowships at the University of Otago and University of California San Francisco. He is a Fellow of American Association of Pharmaceutical Scientists (AAPS) and Fellow of Association of Biotechnology and Pharmacy.

Presented by: Jagdish Singh Professor and Chair of the Department of Pharmaceutical Sciences at North Dakota State University

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