Auckland Cancer Society Research Centre seminar: Perforin – a wellcome perspective Event as iCalendar

31 May 2013

1 - 2pm

Venue: Robb Lecture Theatre, Room 501-B09, Basement Level, Building 501, 85 Park Road, Grafton

The pore-forming protein perforin is a key component in cytotoxic T-lymphocyte- and natural killer cell-mediated immunosurveillance. These cytotoxic cells play a critical role in the elimination of intracellular pathogens and transformed cells, but have also been implicated in various autoimmune disorders, transplant rejection and graft-versus-host disease. As current accepted treatments are associated with a range of side-effects, a new class of a selective immunosuppressive drug which operates via a novel mechanism of action is sought. A small-molecule inhibitor of perforin could fulfil this need by providing a potential treatment for such disorders.

Our current project is funded by the Wellcome Trust, and this seminar will provide an overview of progress during the first year of our three year programme.


: Dr Julie Spicer, Senior Research Fellow, ACSRC

* Open session *

For further information please contact

Jack Flanagan