Molecular Medicine and Pathology seminar series: Studying insulin resistance, genetics and epigenetics of type 2 diabetes Event as iCalendar

15 November 2011

3:30 - 4:30pm

Venue: Seminar Room 501-505, Building 501, 85 Park Road, Grafton

Rising insulin resistance underpins much of the rise in prevalence of type 2 diabetes in recent times, which clearly has a large environmental component. Data demonstrating changes in insulin sensitivity in certain diseases such as beta-blockers used in cirrhosis will be presented and a study with different types of bariatric surgery in obese patients with type 2 diabetes may help identify novel therapeutic interventions. Since people differ in their susceptibility to the obesogenic environment, genetic and epigenetic differences may be associated with this. Low birth weight has been linked with increased risk of insulin resistance and type 2 diabetes later in life. Data on genetic and epigenetic risk factors for insulin resistance in those born small for gestational age will be also be presented.