The research interests of the Department of Medicine at the Waikato Clinical School include Cardiology, Oncology, Endocrinology, Diabetes, Dermatology and Rheumatology. Key academic staff include the Head of Research for the School, Assoc Prof John Conaglen (Endocrinology and Sexual Health), Assoc Prof Peter Jones (Rheumatology), Dr Gerry Devlin (Cardiology), Assoc Prof Amanda Oakley (Dermatology), Mrs Grace Joshy (Research Fellow in Diabetes) and Dr Michael Jameson (Oncology). The Department of Medicine has strong links with AgResearch, Ruakura, and has published a number of papers in conjunction with their researchers.

The group is under the aegis of The University of Auckland's Department of Medicine.