Most people believe that reproduction is a natural right and that they will be able
to reproduce at will. However, for a significant percentage of the population (up
to one in four couples) who suffer from recurrent miscarriage/stillbirth or infertility,
the ability to reproduce is not straight-forward. Many more women suffer from diseases
of pregnancy such as pre-eclampsia and growth retarded babies that result from poor
development of the placenta.
This laboratory's work is focused on investigating the development of the placenta
and interactions between the fetal cells of the placenta (trophoblasts) and the
maternal reproductive system with particular emphasis on interactions with maternal
immune and vascular systems.
We also have a focus on the role of autoantibodies
in causing infertility and placental damage.
Research projects
There are many opportunities for graduate students to join our group. Contact Larry
Chamley for more details.