Principal investigators
Research interests
The research uses advanced optical methods to probe signal transduction pathways
in living cells. In addition to two-photon molecular excitation microscopy, confocal
microscopy and microflourimetry, conventional electrophysiological and immunocytochemical
techniques are used to examine and clarify the inter-relationship among various
components of cellular signal transduction. Previous work has focused on the regulation
of calium release by intracellular stores in a variety of muscle types as well as
early events in fertilisation and metalloproteinase-induced epithelial cell damage.
This group actively collaborates with other groups in the division as well as internationally
with groups in the USA and UK.