Principal investigator
Postgraduate students
- Stacey D'Mello(MSc).
-
Xiaobin Zhan (PhD): (with Professor Bruce Baguley).
Research
Graeme Finlay has worked in the Laboratory of Professor B. C. Baguley in
the Auckland Cancer Society Research Centre. The aim of this project has been in
the area of new drug development. The main interest has been in DNA-binding,
topoisomerase-II-directed drugs, although more recently aspects of the action of
biological response modifiers such as the agent DMXAA (developed in this
laboratory) have been studied.
He co-ordinates courses in Mechanisms of Disease (MEDSCI 203, Semester One) and
in Environmental Threats to Human Health (a first year GE paper, MEDSCI 1010G,
second semester), as well as sharing in cancer teaching at third and fourth year
levels.
An additional interest is in the Public Understanding of Science. He is
concerned at the ongoing ‘evolution-creation’ controversies that are creating
unnecessary frictions in churches and Universities and schools. He believes that
a proper understanding of science and theology removes any basis for
confrontation, and has published extensively to present compelling recent
genetic evidence for evolution, and to show that there is no real basis for
conflict between evolution and the biblical idea of creation.
Faulty research development project
With Dr Ji-Eun Kim" The role of Wnt/b-catenin
signalling in melanoma proliferation and differentiation.
Recent relevant publications
Cancer and drug
development
- Bridewell DJA, Porter ACG, Finlay GJ, and Baguley BC (2008). The role of topoisomerases
and RNA transcription in the action of the antitumour benzonaphthyridine derivative
SN 28049. Cancer Chemother. and Pharmacol. 62 (5):753-62.
- Baguley BC and Finlay GJ (2009). Stem cell niche versus cancer stem cell niche
- differences and similarities. In: Dittmar T and Zänker
KS (Eds.), Stem Cell Biology in Health and Disease. Springer, Berlin.
Science and religion
- Finlay, G.J. 'Homo divinis: the ape that bears God's image'.
Science and Christian Belief 15, 17, 2003.
- Finlay, G.J. 'Evolution as created history'. Science and Christian Belief 20,
67, 2008.
- Finlay, G.J. 'Human evolution: how random process fulfils divine purpose'. Perspectives
on Science and Christian Faith 60(2), 103, 2008.
- Finlay, G.J. 'Human genetics and the image of God', God and Science Paper 2, 2009.
- Finlay, G.J, 'The evidence for evolution'. in Swift
D et al, Debating Darwin
(Milton Keynes: Paternoster Press, 2009).
